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3-Methyl-2-oxobutanoic acid

CAS No. 759-05-7

3-Methyl-2-oxobutanoic acid ( alpha-Ketoisovaleric acid;2-Oxoisovaleric acid )

Catalog No. M19994 CAS No. 759-05-7

alpha-Ketoisovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. alpha-Ketoisovaleric acid is a neurotoxin an acidogen and a metabotoxin.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    3-Methyl-2-oxobutanoic acid
  • Note
    Research use only not for human use.
  • Brief Description
    alpha-Ketoisovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. alpha-Ketoisovaleric acid is a neurotoxin an acidogen and a metabotoxin.
  • Description
    alpha-Ketoisovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. alpha-Ketoisovaleric acid is a neurotoxin an acidogen and a metabotoxin. A neurotoxin causes damage to nerve cells and nerve tissues. alpha-Ketoisovaleric acid is a keto-acid which is a subclass of organic acids. Abnormally high levels of organic acids in the blood (organic acidemia) urine (organic aciduria) the brain and other tissues lead to general metabolic acidosis.
  • Synonyms
    alpha-Ketoisovaleric acid;2-Oxoisovaleric acid
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    759-05-7
  • Formula Weight
    116.12
  • Molecular Formula
    C5H8O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CC(C)C(=O)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yudkoff M et al. Brain amino acid requirements and toxicity: the example of leucine. J Nutr. 2005 Jun;135(6 Suppl):1531S-8S.
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