3-Methyl-2-oxobutanoic acid( alpha-Ketoisovaleric acid | 2-Oxoisovaleric acid )

Catalog No. M19994 CAS No. 759-05-7

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

3-Methyl-2-oxobutanoic acid
Note

Research use only, not for human use.
Brief Description

alpha-Ketoisovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. alpha-Ketoisovaleric acid is a neurotoxin an acidogen and a metabotoxin.
Description

alpha-Ketoisovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. alpha-Ketoisovaleric acid is a neurotoxin an acidogen and a metabotoxin. A neurotoxin causes damage to nerve cells and nerve tissues. alpha-Ketoisovaleric acid is a keto-acid which is a subclass of organic acids. Abnormally high levels of organic acids in the blood (organic acidemia) urine (organic aciduria) the brain and other tissues lead to general metabolic acidosis.
In Vitro

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In Vivo

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Synonyms

alpha-Ketoisovaleric acid | 2-Oxoisovaleric acid
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

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Indication

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1.Yudkoff M et al. Brain amino acid requirements and toxicity: the example of leucine. J Nutr. 2005 Jun;135(6 Suppl):1531S-8S.

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